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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAD1L1
All Species:
21.82
Human Site:
S482
Identified Species:
48
UniProt:
Q9Y6D9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6D9
NP_001013858.1
718
83067
S482
M
E
L
K
M
L
K
S
Q
S
S
S
A
E
Q
Chimpanzee
Pan troglodytes
XP_518933
718
83078
S482
M
E
L
K
M
L
K
S
Q
S
S
S
A
E
Q
Rhesus Macaque
Macaca mulatta
XP_001102100
956
108383
S482
M
E
L
K
M
L
K
S
Q
S
S
S
A
E
Q
Dog
Lupus familis
XP_852066
833
95008
S598
M
E
V
K
M
L
Q
S
Q
S
S
T
A
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTX8
717
83523
A482
M
E
L
K
M
L
K
A
Q
T
S
S
A
E
S
Rat
Rattus norvegicus
NP_001102857
717
83311
A482
M
E
L
K
M
L
R
A
Q
T
S
S
A
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425231
717
83910
S482
V
E
M
K
V
L
K
S
R
E
C
T
A
E
Q
Frog
Xenopus laevis
P10999
583
67273
L361
Q
L
E
E
Y
E
Q
L
L
D
V
K
L
A
L
Zebra Danio
Brachydanio rerio
NP_957206
323
37683
R101
D
L
Q
R
E
I
D
R
N
R
D
L
Q
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796080
709
81997
T472
L
K
D
K
L
T
M
T
K
E
S
L
S
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151757
716
81232
T488
E
L
I
S
H
K
D
T
E
L
N
I
M
N
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
73.1
72.3
N.A.
81
83
N.A.
N.A.
69.9
20.6
27.9
N.A.
N.A.
N.A.
N.A.
33.1
Protein Similarity:
100
99.5
73.8
80.1
N.A.
90.8
92.1
N.A.
N.A.
84.6
40.5
37.7
N.A.
N.A.
N.A.
N.A.
59.3
P-Site Identity:
100
100
100
80
N.A.
80
73.3
N.A.
N.A.
53.3
0
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
13.3
20
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
46.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
19
0
0
0
0
64
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
19
0
0
10
10
0
0
0
0
% D
% Glu:
10
64
10
10
10
10
0
0
10
19
0
0
0
64
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
0
10
0
0
10
% I
% Lys:
0
10
0
73
0
10
46
0
10
0
0
10
0
10
10
% K
% Leu:
10
28
46
0
10
64
0
10
10
10
0
19
10
0
10
% L
% Met:
55
0
10
0
55
0
10
0
0
0
0
0
10
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
10
0
0
0
19
0
55
0
0
0
10
0
46
% Q
% Arg:
0
0
0
10
0
0
10
10
10
10
0
0
0
0
0
% R
% Ser:
0
0
0
10
0
0
0
46
0
37
64
46
10
0
10
% S
% Thr:
0
0
0
0
0
10
0
19
0
19
0
19
0
0
0
% T
% Val:
10
0
10
0
10
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _